What is IGF-1 LR3?
IGF-1 LR3 is a modified, longer-acting version of insulin-like growth factor 1. Its extended half-life and reduced binding-protein affinity make it a research tool for studying IGF-1 signaling, growth and cell proliferation.
Also known as: Long R3 IGF-1
How IGF-1 LR3 is studied
IGF-1 LR3 is a modified, longer-acting version of insulin-like growth factor 1. Changes to its structure extend its half-life and reduce binding to carrier proteins, making it a research tool for studying IGF-1 signaling, growth, and cell proliferation.
Commonly researched for
Research status
Important considerations
Affects blood sugar and cell growth pathways; potential risks around proliferation. Not an approved therapy.
IGF-1 LR3 — frequently asked questions
IGF-1 signaling, cell proliferation, and body composition — largely as a research reagent.
The "Long R3" modifications extend its duration of action and reduce binding-protein affinity compared with native IGF-1.
It affects blood sugar and cell-growth pathways, with potential proliferation-related risks. It is not an approved therapy and human safety data is limited.