Kisspeptin-10 (also known as KP-10, Metastin fragment) is a hypothalamic peptide studied for its role in reproductive hormone signaling. This page covers what the published research does — and does not — establish about it in relation to libido and sexual health.
Kisspeptin-10 is researched for Libido studies — which is why it appears in discussions of libido and sexual health.
Research status: Human research in reproductive endocrinology.
How Kisspeptin-10 is thought to work
Kisspeptin-10 is a fragment of kisspeptin, a hypothalamic peptide that sits at the top of the reproductive hormone axis by stimulating GnRH release. It is studied in fertility and reproductive endocrinology, including as a way to probe or support the hormone axis.
What it does not establish
Affects the reproductive endocrine axis. Research/clinical context only.
Nothing on this page is a recommendation to use Kisspeptin-10, and Selpho publishes no dosing, reconstitution or sourcing information. Read how we decide what goes in the library.
Other peptides researched for Libido
A synthetic form of GnRH used to stimulate pituitary hormone release.
Frequently asked questions
Human research in reproductive endocrinology. Research relevant to this area covers libido studies. That is a description of where the research points, not evidence that it will work for you — and Selpho does not provide dosing or medical advice.
Human research in reproductive endocrinology.
Affects the reproductive endocrine axis. Research/clinical context only. Always speak to a licensed healthcare professional before considering any peptide.
Reproductive hormone signaling, fertility research, and some libido studies. It acts upstream of GnRH.
It stimulates GnRH release from the hypothalamus, which in turn drives LH and FSH — a key upstream control point.
Is Kisspeptin-10 right for your situation?
Describe your goals and the free Peptide Advisor will match them against the research — no signup, no sales pitch.
Ask the Advisor — freeThis page is for educational purposes only and is not medical advice, a diagnosis, or a recommendation to use any compound. It contains no dosing or purchase information. Always consult a licensed healthcare professional before considering any peptide.