Cognitive & Mood

Semax

A neuropeptide studied for cognition and neuroprotection.

What is Semax?

Semax is a synthetic peptide derived from a fragment of ACTH, developed in Russia and researched for cognitive enhancement and neuroprotection, including in the context of stroke recovery in regional clinical studies.

Also known as: ACTH 4-10 analog

Read the in-depth Semax guide

How Semax is studied

Semax is a synthetic peptide derived from a fragment of ACTH, developed in Russia and studied for cognitive and neuroprotective effects. Research points to influence on BDNF and other neurotrophic factors, and it has been used in regional clinical settings including stroke recovery.

Commonly researched for

Memory & focusNeuroprotectionStroke recovery studies

Typically stacked with

Selank

Research status

Primarily Russian clinical and preclinical research.

Important considerations

Evidence is largely region-specific. Not an approved medication in the US/EU.

View published research on PubMed

Semax — frequently asked questions

Memory and focus, neuroprotection, and — in regional clinical studies — stroke recovery. Evidence is largely region-specific.

No. It is not an approved medication in the US or EU. Much of the clinical use and research is based in Russia.

They are often discussed together as Russian-developed neuropeptides, but Semax leans cognitive/neuroprotective while Selank leans anxiolytic.

This page is for educational purposes only and is not medical advice, a diagnosis, or a recommendation to use any compound. It contains no dosing or purchase information. Always consult a licensed healthcare professional before considering any peptide.