Metabolic

AOD-9604

A growth-hormone fragment studied for fat metabolism.

What is AOD-9604?

AOD-9604 is a modified fragment of the C-terminus of human growth hormone (176-191). It was investigated for fat-burning (lipolytic) effects without the growth-promoting activity of full-length GH.

Also known as: Anti-Obesity Drug 9604, hGH fragment 176-191

Read the in-depth AOD-9604 guide

How AOD-9604 is studied

AOD-9604 is a modified fragment of the C-terminus of human growth hormone (residues 176-191). It was designed to stimulate fat metabolism (lipolysis) without the growth-promoting or blood-sugar effects of full-length growth hormone.

Commonly researched for

Fat metabolismBody compositionCartilage/joint studies

Research status

Human trials for obesity did not meet primary endpoints; further research ongoing.

Important considerations

Weight-loss efficacy was not established in clinical trials. Not an approved therapy.

View published research on PubMed

AOD-9604 — frequently asked questions

Fat metabolism and body composition, with some interest in cartilage and joint research.

Human obesity trials did not meet their primary weight-loss endpoints, so efficacy for weight loss is not established.

No. It is not an approved therapy for these uses; further research is ongoing.

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