What is MOTS-c?
MOTS-c is a peptide encoded in mitochondrial DNA that acts as a metabolic regulator. Research has explored its role in insulin sensitivity, metabolic homeostasis and exercise capacity.
Also known as: Mitochondrial ORF of the 12S rRNA type-c
Commonly researched for
Research status
Preclinical research; early human interest.
Important considerations
Mostly studied in animal and cell models. Human data is emerging.