What is MK-677?
MK-677 (ibutamoren) is an orally active, long-acting growth-hormone secretagogue. Although not a peptide itself, it is commonly grouped with GH peptides because it raises GH and IGF-1 by mimicking ghrelin.
Also known as: Ibutamoren, Ibutamoren mesylate
How MK-677 is studied
MK-677 (ibutamoren) is an orally active, long-acting growth-hormone secretagogue. Although technically a non-peptide, it is grouped with GH peptides because it mimics ghrelin to raise growth hormone and IGF-1 levels.
Commonly researched for
Research status
Important considerations
Can increase appetite, water retention and blood sugar. Technically a non-peptide secretagogue.
MK-677 — frequently asked questions
Not exactly — it is a non-peptide secretagogue, but it is commonly grouped with GH peptides because it raises GH and IGF-1 by mimicking ghrelin.
Growth hormone and IGF-1 levels, sleep, body composition, and bone density. It has been investigated in human trials.
Studies note increased appetite, water retention, and effects on blood sugar. It is not approved for these uses.