What is KPV?
KPV is the C-terminal tripeptide of the alpha-melanocyte-stimulating hormone (α-MSH). Research has focused on its anti-inflammatory properties, particularly in the context of the gut and skin.
Also known as: Lysine-Proline-Valine, α-MSH 11-13
How KPV is studied
KPV is the C-terminal tripeptide (lysine-proline-valine) of the hormone α-MSH. Research suggests it carries much of α-MSH's anti-inflammatory activity — potentially acting inside cells to dampen inflammatory signaling — which is why it is studied in gut and skin inflammation models.
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Research status
Important considerations
Human clinical data is limited. Studied mostly in cell and animal models.
KPV — frequently asked questions
Anti-inflammatory effects, particularly in the gastrointestinal tract and skin, plus general immune modulation. Evidence is mostly preclinical.
No. KPV is a small peptide fragment of α-MSH, not a corticosteroid. It is studied for anti-inflammatory activity through different pathways.
Human clinical data is limited; most research is in cell and animal models.