LL-37 (also known as Cathelicidin, CAP-18) is the human cathelicidin antimicrobial peptide studied for immune defense. This page covers what the published research does — and does not — establish about it in relation to gut health and digestive repair.
LL-37 is discussed in the context of gut health and digestive repair because of its mechanism, not because the literature studies it for that outcome directly. The research we can point to covers Antimicrobial defense, Wound healing, Immune modulation. Treat any claim beyond that with scepticism.
Research status: Active area of preclinical research.
How LL-37 is thought to work
LL-37 is the active form of the human cathelicidin antimicrobial peptide, a part of the innate immune system. Research covers its antimicrobial activity, roles in wound healing, and immune modulation — though at high levels it has also been linked to inflammatory conditions.
What it does not establish
At high levels it has been linked to inflammatory conditions in research. Human therapeutic data is limited.
Nothing on this page is a recommendation to use LL-37, and Selpho publishes no dosing, reconstitution or sourcing information. Read how we decide what goes in the library.
Other peptides researched for Gut Health
A short tripeptide fragment of α-MSH studied for anti-inflammatory effects.
Frequently asked questions
Not directly. LL-37 is discussed in the context of gut health and digestive repair because of its mechanism, but the research we can point to studies it for antimicrobial defense, wound healing, immune modulation rather than for this outcome specifically. Active area of preclinical research. Selpho does not provide dosing or medical advice.
Active area of preclinical research.
At high levels it has been linked to inflammatory conditions in research. Human therapeutic data is limited. Always speak to a licensed healthcare professional before considering any peptide.
Antimicrobial defense, wound healing, and immune modulation. It is an active area of preclinical research.
Not necessarily — while it supports immune defense, elevated levels have been associated with certain inflammatory conditions in research.
Is LL-37 right for your situation?
Describe your goals and the free Peptide Advisor will match them against the research — no signup, no sales pitch.
Ask the Advisor — freeThis page is for educational purposes only and is not medical advice, a diagnosis, or a recommendation to use any compound. It contains no dosing or purchase information. Always consult a licensed healthcare professional before considering any peptide.