Sermorelin (also known as GRF 1-29, GHRH 1-29) is one of the earliest GHRH analogs, historically used to assess GH function. This page covers what the published research does — and does not — establish about it in relation to growth-hormone support.
Sermorelin is researched for Growth hormone support, Age-related GH decline — which is why it appears in discussions of growth-hormone support.
Research status: Historical clinical use; well-characterized pharmacology.
How Sermorelin is thought to work
Sermorelin consists of the first 29 amino acids of GHRH — the active core of the hormone. It stimulates natural growth-hormone secretion and has a long clinical history, having been used diagnostically to evaluate pituitary growth-hormone function.
What it does not establish
Endocrine-active. Should only be considered under medical supervision.
Nothing on this page is a recommendation to use Sermorelin, and Selpho publishes no dosing, reconstitution or sourcing information. Read how we decide what goes in the library.
Commonly researched alongside
A selective growth-hormone secretagogue studied for its clean GH-release profile.
Other peptides researched for Growth Hormone
A growth-hormone-releasing hormone analog studied for GH support.
A selective growth-hormone secretagogue studied for its clean GH-release profile.
A GHRH analog approved for HIV-associated lipodystrophy and studied for visceral fat.
An early GH-releasing peptide known for strongly stimulating appetite.
A potent GH secretagogue also studied for cardiac tissue effects.
An orally active growth-hormone secretagogue (a non-peptide) studied for GH/IGF-1.
Frequently asked questions
Historical clinical use; well-characterized pharmacology. Research relevant to this area covers growth hormone support, age-related gh decline. That is a description of where the research points, not evidence that it will work for you — and Selpho does not provide dosing or medical advice.
Historical clinical use; well-characterized pharmacology.
Endocrine-active. Should only be considered under medical supervision. Always speak to a licensed healthcare professional before considering any peptide.
Supporting the body's own growth-hormone production, with interest in sleep quality and age-related GH decline. It has historical diagnostic use.
Both are GHRH analogs; CJC-1295 is engineered for a longer duration of action. Both are endocrine-active and should be used under medical supervision.
Is Sermorelin right for your situation?
Describe your goals and the free Peptide Advisor will match them against the research — no signup, no sales pitch.
Ask the Advisor — freeThis page is for educational purposes only and is not medical advice, a diagnosis, or a recommendation to use any compound. It contains no dosing or purchase information. Always consult a licensed healthcare professional before considering any peptide.