Metabolic

Survodutide

An investigational GLP-1/glucagon dual agonist studied for weight and liver health.

What is Survodutide?

Survodutide is a dual agonist of the GLP-1 and glucagon receptors under investigation for obesity and metabolic-associated fatty liver disease (MASH). It combines appetite regulation with effects on energy expenditure.

Also known as: BI 456906

Read the in-depth Survodutide guide

How Survodutide is studied

Survodutide is an investigational dual agonist of the GLP-1 and glucagon receptors. Combining appetite regulation with glucagon-driven energy expenditure, it is under study for obesity and for metabolic-associated fatty liver disease (MASH).

Commonly researched for

Weight managementLiver health (MASH)Metabolic health

Research status

Clinical trials — investigational.

Important considerations

Not approved. Investigational compound; use only under medical supervision.

View published research on PubMed

Survodutide — frequently asked questions

Weight management, liver health (MASH), and broader metabolic outcomes. It is investigational.

It activates both GLP-1 and glucagon receptors, whereas semaglutide targets GLP-1 alone. It is still in clinical development.

No. It is investigational and not approved for use.

This page is for educational purposes only and is not medical advice, a diagnosis, or a recommendation to use any compound. It contains no dosing or purchase information. Always consult a licensed healthcare professional before considering any peptide.