Survodutide (also known as BI 456906) is an investigational GLP-1/glucagon dual agonist studied for weight and liver health. This page covers what the published research does — and does not — establish about it in relation to fat loss and weight management.
Survodutide is researched for Weight management, Metabolic health — which is why it appears in discussions of fat loss and weight management.
Research status: Clinical trials — investigational.
How Survodutide is thought to work
Survodutide is an investigational dual agonist of the GLP-1 and glucagon receptors. Combining appetite regulation with glucagon-driven energy expenditure, it is under study for obesity and for metabolic-associated fatty liver disease (MASH).
What it does not establish
Not approved. Investigational compound; use only under medical supervision.
Nothing on this page is a recommendation to use Survodutide, and Selpho publishes no dosing, reconstitution or sourcing information. Read how we decide what goes in the library.
Other peptides researched for Fat Loss
A GLP-1 receptor agonist approved for type 2 diabetes and weight management.
A dual GIP/GLP-1 receptor agonist approved for diabetes and weight management.
An investigational triple GIP/GLP-1/glucagon agonist studied for weight loss.
A long-acting amylin analog studied for appetite and weight, often with semaglutide.
Frequently asked questions
Clinical trials — investigational. Research relevant to this area covers weight management, metabolic health. That is a description of where the research points, not evidence that it will work for you — and Selpho does not provide dosing or medical advice.
Clinical trials — investigational.
Not approved. Investigational compound; use only under medical supervision. Always speak to a licensed healthcare professional before considering any peptide.
Weight management, liver health (MASH), and broader metabolic outcomes. It is investigational.
It activates both GLP-1 and glucagon receptors, whereas semaglutide targets GLP-1 alone. It is still in clinical development.
Is Survodutide right for your situation?
Describe your goals and the free Peptide Advisor will match them against the research — no signup, no sales pitch.
Ask the Advisor — freeThis page is for educational purposes only and is not medical advice, a diagnosis, or a recommendation to use any compound. It contains no dosing or purchase information. Always consult a licensed healthcare professional before considering any peptide.