Humanin (also known as HN, MTRNR2) is a mitochondrial-derived peptide studied for cytoprotection and aging. This page covers what the published research does — and does not — establish about it in relation to anti-aging and longevity.
Humanin is discussed in the context of anti-aging and longevity because of its mechanism, not because the literature studies it for that outcome directly. The research we can point to covers Cytoprotection, Metabolic health, Neuroprotection. Treat any claim beyond that with scepticism.
Research status: Preclinical research; emerging human interest.
How Humanin is thought to work
Humanin is a mitochondrial-derived peptide with cytoprotective properties. Research has explored roles in metabolism, neuroprotection, and age-related conditions, making it a subject of interest in longevity science.
What it does not establish
Mostly studied in cell and animal models. Human data is early.
Nothing on this page is a recommendation to use Humanin, and Selpho publishes no dosing, reconstitution or sourcing information. Read how we decide what goes in the library.
Commonly researched alongside
Other peptides researched for Anti-Aging
A mitochondria-targeting peptide studied for cellular energy and disease.
A copper-binding tripeptide extensively studied in skin and hair research.
Frequently asked questions
Not directly. Humanin is discussed in the context of anti-aging and longevity because of its mechanism, but the research we can point to studies it for cytoprotection, metabolic health, neuroprotection rather than for this outcome specifically. Preclinical research; emerging human interest. Selpho does not provide dosing or medical advice.
Preclinical research; emerging human interest.
Mostly studied in cell and animal models. Human data is early. Always speak to a licensed healthcare professional before considering any peptide.
Cytoprotection, metabolic health, and neuroprotection, mostly in cell and animal models.
A peptide encoded within mitochondrial DNA — a relatively new area of biology that includes Humanin and MOTS-c.
Is Humanin right for your situation?
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Ask the Advisor — freeThis page is for educational purposes only and is not medical advice, a diagnosis, or a recommendation to use any compound. It contains no dosing or purchase information. Always consult a licensed healthcare professional before considering any peptide.